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15.Estrogens should be used with caution in individuals with severe hypocalcaemia.
Get emergency medical help if you have signs of an allergic reaction to Premarinhivesdifficult breathingswelling of your facelipstongueor throat.
Use of estrogen-aloneor in combination with a progestinshould be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual womanPostmenopausal women should be re-evaluated periodically as clinically appropriate to determine if treatment is still necessary.
Estrogens may cause some degree of fluid retentionWomen with conditions that might be influenced by this factorsuch as cardiac or renal dysfunctionwarrant careful observation when estrogen-alone is prescribed.
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however, wyeth-ayerst laboratories decided to market premarin as natural because of the animal source, rather than on its biochemical nature.
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