Precose hypoglycemia alpha glucosidase inhibitors.
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Clinical Experience in Type 2 Diabetes Mellitus Patients on Monotherapyor in Combination with SulfonylureasMetformin or InsulinPrecose was studied as monotherapy and as combination therapy to sulfonylureametforminor insulin treatmentThe treatment effects on HbA1c levels and one-hour postprandial glucose levels are summarized for four placebo-controlleddouble-blindrandomized studies conducted in the United States in Tables 2 and 3respectivelyThe placebo-subtracted treatment differenceswhich are summarized belowwere statistically significant for both variables in all of these studies.
Acarbose is a prescription oral drug that is used to control blood glucosesugarlevels in people type 2 diabetes in conjunction with dietexerciseand other diabetes drugsfor examplemetforminGlucophageor insulinIt belongs to a class of drugs called alpha-glucosidase inhibitorswhich also includes miglitolGlysetCarbohydrates that are eaten are digested by enzymes in the intestine into smaller sugars which are absorbed into the body and increase blood sugar levelsThe process of carbohydrate digestion requires the pancreas to release into the intestine alpha-amylase enzymeswhich digest the large carbohydrates into smaller carbohydrates called oligosaccharidesThe cells lining the small intestine then release alpha-glucosidase enzymes that further digest the oligosaccharides into smaller sugarslike glucosethat can be absorbedAcarbose is a man-made oligosaccharide designed to slow down the actions of alpha-amylase and alpha-glucosidase enzymesthereby slowing the appearance of sugar in the blood after a meal.
Because its mechanism of action is differentthe effect of Precose to enhance glycemic control is additive to that of sulfonylureasinsulin or metformin when used in combinationIn additionPrecose diminishes the insulinotropic and weight-increasing effects of sulfonylureas.
Take exactly as prescribed by your doctorDo not take in larger or smaller amounts or for longer than recommendedFollow the directions on your prescription label.
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precose is renowned in the healthcare system as a very potent medication with a great control over diabetes.
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