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Fanconi’s syndrome is characterized by renal glycosuriaphosphaturiaaminoaciduriaand acidosis with or without proteinuria and ricketsIt is associated with the ingestion of outdated or degraded tetracyclineAdditionallyprevious formulations of tetracycline contained citric acid which may contribute to metabolic acidosishowevercurrent formulations of the drug do notPatients generally require hospitalization with intravenous medication to correct the accompanying metabolic abnormalitiesMost cases resolve over time after discontinuation of tetracycline without permanent sequelaePatients should be instructed to discard any unused portions of tetracycline at the end of therapy and to never use tetracycline remaining from a previous prescriptionRef]
Continue to take this medication until the full-prescribed amount is finished even if symptoms disappear after a few daysStopping the medication too early may allow bacteria to continue to growwhich may result in a relapse of the infection.
Take this medication 2-3 hours before or after taking any products containing magnesiumaluminumor calciumSome examples include antacidsquinaprilcertain forms of didanosinechewable/dispersible buffered tablets or pediatric oral solutionvitamins/mineralsand sucralfateFollow the same instructions with dairy productse.gmilkyogurtcalcium-enriched juicebismuth subsalicylateironand zincThese products bind with tetracyclinepreventing its full absorption.
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