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Us ACTOPLUS MT should b tmpoaily suspndd any sugical pocdu (xcpt minpocdus not associatd with stictd intak ood and luids) and should not b statd until th patint’s oal intak has sumd and nal unction has bn valuatd as nomal.
Pioglitazon hydochloid was not mutagnic in a batty gntic toxicology studis, including th Ams bactial assay, a mammalian cll owad gn mutation assay (CHO/HPT and AS52/XPT), an in vitcytogntics assay using CHL clls, an unschduld DNA synthsis assay, and an in vivmiconuclus assay.
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Patints whhav sum ALT gat than th tims th nc ang with sum total biliubin gat than twtims th nc ang without altnativ tiologis a at isk sv dug-inducd liv injuy, and should not b statd on ACTOPLUS MT. patints with lss lvations sum ALT biliubin and with an altnat pobabl caus, tatmnt with ACTOPLUS MT can b usd with caution.
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