Asparaginase erwinia chrysanthemi major l-asparaginase with methotrexate has shown both therapeutic synergistic and antagonistic effects depending upon the schedule of administration of these agents.

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Information about Methotrexate.

Many drugs can interact with methotrexateThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed hereTell your doctor about all your current medicines and any medicine you start or stop using.

If you need to be sedated for dental worktell your dentist you currently use this medicine.

For psoriasismethotrexate slows down how fast your body produces the top layer of your skinThis helps to treat the symptoms of psoriasiswhich include dryitchy patches of skin.

This medicine may affect fertilityability to have childrenin both men and womenHoweverit is important to use birth control to prevent pregnancy because methotrexate may harm the baby if a pregnancy does occur.

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