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KEPPRA can cause hematologic abnormalitiesHematologic abnormalities occurred in clinical trials and included decreases in white blood cellWBCneutrophiland red blood cellRBCcountsdecreases in hemoglobin and hematocritand increases in eosinophil countsCases of agranulocytosispancytopeniaand thrombocytopenia have been reported in the postmarketing settingA complete blood count is recommended in patients experiencing significant weaknesspyrexiarecurrent infectionsor coagulation disorders.
The use of levetiracetam has been very rarely associated with acute kidney injurywith a time to onset ranging from a few days to several months.
When using the oral solution in pediatric patientsdosing is weight-basedmg per kgusing a calibrated measuring devicenot a household teaspoon or tablespoon
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