Doxepin is primarily metabolized by cyp2c19 and cyp2d6, and use of isoniazid, a potent inhibitor of cyp2c19, may result in increased doxepin plasma concentrations and subsequent adverse reactions.
Information about Isoniazid.
Isoniazid is a bactericidal agent active against organisms of the genus Mycobacteriumspecifically MtuberculosisMbovis and MkansasiiIt is a highly specific agentineffective against other microorganismsIsoniazid is bactericidal to rapidly-dividing mycobacteriabut is bacteriostatic if the mycobacterium is slow-growing.
If you experience any of the following serious side effectsstop taking isoniazid and seek emergency medical attention or contact your doctor immediately:
Before taking isoniazidtell your doctor if you are taking any of the following drugs:
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