Since the last-named enzyme is acts as a reductase fosamax 35mg otc, regenerating active glucocorticoids, not detectable in other steroid-producing tissues, the whereas 11 -hsd-2 acts as a dehydrogenase, convert- term 11-oxygenated steroids is considered synonymous ing cortisol to its inactive 11-keto derivative cortisone .
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Merck also faced scrutiny for its controversial marketing practices of the drugThese practices include using misleading ads and publishing fake journal articles.
Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapyradiationor steroidsOther risk factors include blood clotting disordersanemialow red blood cellsand a pre existing dental problem.
UsesTreatment to increase bone mass and reduce the incidence of fractures including hip and spinevertebral compression fracturesin postmenopausal women with osteoporosisTreatment to increase bone mass in men with osteoporosisTreatment of glucocorticoid-induced osteoporosis in men and women receiving glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and who have low bone mineral density.
Alendronate is used to prevent and treat certain types of bone lossosteoporosisin adultsOsteoporosis causes bones to become thinner and break more easilyYour chance of developing osteoporosis increases as you ageafter menopauseor if you are taking corticosteroid medicationssuch as prednisonefor a long time.
9Chesnut CH 3rdMcClung MREnsrud KEBell NHGenant HKHarris STSinger FRStock JLYood RADelmas PDet alAlendronate treatment of the postmenopausal osteoporotic womaneffect of multiple dosages on bone mass and bone remodelingAm J Med 991995144-52.
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