If you regularly consume alcohol you should talk to a doctor before taking cymbalta.

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Tell your doctor about any other medical conditions you may haveThe drug should be prescribed with caution in those who have:

The most commonly observed adverse reactions in CYMBALTA-treated patientsas defined abovewere nauseadry mouthconstipationsomnolencedecreased appetitehyperhidrosisand agitation.

Some patients taking Cymbalta have developed liver problemsIn rare casesthis has lead to liver failure and deathContact your health care provider immediately if you develop any of the following symptoms while taking Cymbalta:

CYMBALTA treatment in placebo-controlled clinical trials across approved indicationswas associated with small mean increases from baseline to endpoint in ALTASTCPKand alkaline phosphataseinfrequentmodesttransientabnormal values were observed for these analytes in CYMBALTA-treated patients when compared with placebo-treated patientssee WARNINGS AND PRECAUTIONSHigh bicarbonatecholesteroland abnormalhigh or lowpotassiumwere observed more frequently in CYMBALTA treated patients compared to placebo.

Table 2Treatment-Emergent Adverse ReactionsIncidence of 5or More and Greater than Placebo in Placebo-Controlled Trials of Approved Indications a.

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