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It is not known whether selegiline passes into breast milk or if it could harm a nursing babyTell your doctor if you are breast-feeding a baby.

Severe CNS toxicityserotonin syndromehas been reported in patients with the combination of tricyclic antidepressants and selegilineIn one patient receiving amitriptyline and selegiline this included hyperpyrexia and deathand another patient receiving protriptyline and selegiline experienced tremoragitationand restlessness followed by unresponsiveness and death two weeks after selegiline was added.

Selegiline should not be used in patients who are being treated with antidepressant drugsincluding MAO inhibitorstricyclic antidepressantsserotonin noradrenaline reuptake inhibitorsSNRIvenlafaxineand selective serotonin reuptake inhibitorse.g citalopramescitalopramfluoxetinefluvoxamineparoxetine and sertralineSee section 4.5 interactions

Fresh meatpoultryor fishincluding lunch meathot dogsbreakfast sausageand cooked sliced ham

Selegiline may be administered either as a single dose in the morning or in two divided doses of 5 mgtaken at breakfast and lunch.

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