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Skelaxin can cause side effects that may impair your thinking or reactionsBe careful if you drive or do anything that requires you to be awake and alertAvoid drinking alcoholIt can increase some of the side effects of metaxalone.

Reproduction studies in rats have not revealed evidence of impaired fertility or harm to the fetus due to metaxalonePost marketing experience has not revealed evidence of fetal injurybut such experience cannot exclude the possibility of infrequent or subtle damage to the human fetusSafe use of metaxalone has not been established with regard to possible adverse effects upon fetal developmentThereforemetaxalone tablets should not be used in women who are or may become pregnant and particularly during early pregnancy unlessin the judgement of the physicianthe potential benefits outweigh the possible hazards.

In conjunction with the UVAR photopheresis to treat diffuse systemic sclerosis.

Metaxalone has no direct action on the contractile mechanism of striated musclethe motor end plateor the nerve fiber.

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