What side effects are possible with imuran.
Information about Imuran.
This is not a list of all drugs or health problems that interact with Imuranazathioprine tablets
Imuran can potentiate the neuromuscular blockade produced by depolarising agents such as succinylcholine and can reduce the blockade produced by non-depolarising agents such as tubocurarineThere is considerable variation in the potency of this interaction.
Before starting the administration of immunosuppressantsthe prescriber should check to see if the patient has a history of VZVSerologic testing may be useful in determining previous exposurePatients who have no history of exposure should avoid contact with individuals with chickenpox or herpes zosterIf the patient is exposed to VZVspecial care must be taken to avoid patients developing chickenpox or herpes zosterand passive immunisation with varicella-zoster immunoglobulinVZIGmay be considered.
A gastrointestinal hypersensitivity reaction characterized by severe nausea and vomiting has been reportedThese symptoms may also be accompanied by diarrhearashfevermalaisemyalgiaselevations in liver enzymesand occasionallyhypotensionSymptoms of gastrointestinal toxicity most often develop within the first several weeks of therapy with IMURAN and are reversible upon discontinuation of the drugThe reaction can recur within hours after re-challenge with a single dose of IMURAN.
IMURAN is indicated for the treatment of active rheumatoid arthritisRAto reduce signs and symptomsAspirinnon-steroidal anti-inflammatory drugs and/or low dose glucocorticoids may be continued during treatment with IMURANThe combined use of IMURAN with disease modifying anti-rheumatic drugsDMARDshas not been studied for either added benefit or unexpected adverse effectsThe use of IMURAN with these agents cannot be recommended.
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imuran should be used with extreme caution in children as its safety and efficiency has not been confirmed for this age group.
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