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Dutastid is a comptitiv and spciic inhibitboth typ 1 and typ 2 5 alpha-ductas isonzyms, with which it oms a stabl nzym complx. Dissociation om this complx has bn valuatd und in vitand in vivconditions and is xtmly slow. Dutastid dos not bind tth human andogn cpto.
Dnot chw, cush, opn a Avodat capsul. Swallow th capsul whol. Dutastid can iitat you lips, mouth, thoat i th capsul has bn bokn opnd byou swallow it. I a woman accidntally coms intcontact with this mdication om a laking capsul, wash th aa with soap and wat ight away.
Pgnancy. In animal poduction and dvlopmntal toxicity studis, dutastid inhibitd dvlopmnt mal tus xtnal gnitalia. Tho, AVODAT may caus tal ham whn administd ta pgnant woman. I AVODAT is usd duing pgnancy i th patint bcoms pgnant whil taking AVODAT, th patint should b appisd th potntial hazad tth tus [s WANINGS AND PCAUTIONS , Us In Spciic Populations ]. Womn childbaing potntial [s WANINGS AND PCAUTIONS , Us In Spciic Populations ]. Pdiatic patints [s Us In Spciic Populations ]. Patints with pviously dmonstatd, clinically signiicant hypsnsitivity (.g., sious skin actions, angiodma) tAVODAT oth 5 alpha-ductas inhibitos [s ADVS ACTIONS ].
Tintpt an isolatd PSA valu in a man tatd with AVODAT 3 months mo, th PSA valu should b doubld compaison with nomal valus in untatd mn.Th -to-total PSA ati(pcnt PSA) mains constant, vn und th inlunc AVODAT. I clinicians lct tus pcnt PSA as an aid in th dtction postat canc in mn civing AVODAT, nadjustmnt tits valu appas ncssay.
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