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Increased risk of lactic acidosis with topiramateother carbonic anhydrase inhibitorsegzonisamideacetazolamidedichlorphenamidemonitorConcomitant cationic drugs that interfere with renal tubular transport systemsegranolazinevandetanibdolutegravircimetidinemay increase metformin levelsmonitorAvoid excessive alcohol intakepotentiates effects of metformin on lactateDiureticssteroidsphenothiazinesthyroid productsestrogensoral contraceptivesphenytoinsympathomimeticscalcium channel blockersisoniazidnicotinic acidothers may cause hyperglycemiaMay need lower dose of concomitant insulin and/or insulin secretagogueegsulfonylureato reduce risk of hypoglycemia.
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Follow your doctor’s instructions about using this medicine if you are pregnantBlood sugar control is very important during pregnancyand your dose needs may be different during each trimester of pregnancyTell your doctor if you become pregnant while taking Glucophage.
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugarIt is used in patients with type 2 diabetesControlling high blood sugar helps prevent kidney damageblindnessnerve problemsloss of limbsand sexual function problemsProper control of diabetes may also lessen your risk of a heart attack or strokeMetformin works by helping to restore your body’s proper response to the insulin you naturally produceIt also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.
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the glucophage xr tablet is made with a shell that is not absorbed or melted in the body.
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