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Glimepiride belongs to a class of drugs known as sulfonylureasIt works by causing the release of your body’s natural insulin.
Pioglitazone may rarely cause or worsen a certain heart problemheart failureTell your doctor right away if you notice any symptoms of heart failureincludingshortness of breathswelling ankles/feetunusual tirednessunusual/sudden weight gain.
Carefully follow the special diet your doctor gave youThis is the most important part of controlling your diabetes and will help the medicine work properlyExercise regularly and test for sugar in your blood or urine as directed.
Duetact may not work as well when you use other medicines at the same timeThis includes prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed hereTell your doctor about all medicines you start or stop using.
Pioglitazone hydrochloridea component of glimepiride/pioglitazone hydrochloridemay cause or exacerbate congestive heart failuremonitor patients for signs and symptoms of heart failure after initiation or dose increaseShould heart failure developmanage according to current standards of careConsider discontinuation or dose reductionGlimepiride/pioglitazone hydrochloride is not recommended in patients with symptomatic heart failure and is contraindicated in established NYHA Class III or IV heart failure
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