On the other hand, if a patient is stabilised on clozaril and not treatment refractory, then cautious switching to a generic formulation may be reasonable.

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If you are using the liquid form of this medicationread the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refillIf you have any questionsask your doctor or pharmacist.

Long-acting depot antipsychoticswhich have myelosuppressive potentialmust not be used concurrently with Clozaril because these cannot be rapidly removed from the body in situations where this may be requirede.gneutropeniasee section 4.3

Data from two large observational studies showed that elderly people with dementia who are treated with antipsychotics are at a small increased risk of death compared with those who are not treatedThere are insufficient data to give a firm estimate of the precise magnitude of the risk and the cause of the increased risk is not known.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythmBefore using clozapinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death

Liquid products or dissolving tablets may contain sugar and/or aspartameLiquid products may also contain alcoholCaution is advised if you have diabetesliver diseasephenylketonuriaPKUor any other condition that requires you to limit/avoid these substances in your dietAsk your doctor or pharmacist about using this product safely.

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