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Nauseaconstipationflatulenceabdominal paindiarrheaheadachedizzinessedemarashcardiovascular thrombotic eventsGI ulcer/bleedhepatotoxicityrenal toxicityhypertensionhypersensitivity reactionsanemia/blood dyscrasias.

Older adults may be more sensitive to the side effects of this drugespecially stomach/intestinal bleeding and kidney problems.

Digestive SystemDyspepsiaelevated liver enzymesgross bleeding/perforationheartburnulcersgastric/duodenaldry mouthesophagitisgastritisglossitishematemesishepatitisjaundicemelenarectal bleedingeructationliver failurepancreatitis.

Additionallyfluid retention and edema have been observed in some patients treated with NSAIDsUse of piroxicam may blunt the CV effects of several therapeutic agents used to treat these medical conditionse.gdiureticsACE inhibitorsor angiotensin receptor blockersARBssee DRUG INTERACTIONS

After observing the response to initial therapy with FELDENEthe dose and frequency should be adjusted to suit an individual patient’s needs.

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