In addition, in patients with severe hepatic cirrhosis, the bupropion c max and auc were substantially increased mean difference by approximately 70 and 3-fold, respectively and more variable when compared to values in healthy volunteers; the mean bupropion half-life was also longer 29 hours in patients with severe hepatic cirrhosis vs 19 hours in healthy subjects .
Information about Bupropion.
This medication contains bupropionDo not take WellbutrinZybanBudeprion SRAplenzinBuprobanWellbutrin SRWellbutrin XLor Forfivo XL if you are allergic to bupropion or any ingredients contained in this drug.
This medication contains bupropionDo not take WellbutrinZybanBudeprion SRAplenzinBuprobanWellbutrin SRWellbutrin XLor Forfivo XL if you are allergic to bupropion or any ingredients contained in this drug.
XL and SR tablets are intended for oral use only Inhaling crushed tablets or injecting dissolved tablets has been reported to cause seizures and/or death.
Monoamine oxidase inhibitorsMAOIssuch as phenelzine or selegilineUsing these drugs with bupropion can result in severe high blood pressureAt least 14 days should pass between your use of an MAOI and use of bupropion.
No matter what your agebefore you take an antidepressantyouyour parentor your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatmentsYou should also talk about the risks and benefits of not treating your conditionYou should know that having depression or another mental illness greatly increases the risk that you will become suicidalespecially at the beginning of your treatment or any time that your dose is increased or decreasedThis risk is higher if you or anyone in your family has or has ever had bipolar disorder or mania or has thought about or attempted suicideTalk to your doctor about your conditionsymptomsand personal and family medical historyYou and your doctor will decide what type of treatment is right for you.
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table 6 presents the incidence of body weight changes 5 lbs in the 3 sad trials using bupropion hcl extended-release.
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