Atrovent is indicated for use inpatients with chronic obstructive pulmonary disease copd on a regularaerosol bronchodilator who continue to have evidence of bronchospasmand who require a second bronchodilator.
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Ipatopium bomid is a quatnay ammonium compound with anticholingic (paasympatholytic) poptis. In nonclinical studis, it appas tinhibit vagally mdiatd lxs by antagonising th action actylcholin, th tansmitt agnt lasd om th vagus nv. Anticholingics pvnt th incas in intacllula concntation Ca++ which is causd by intaction actylcholin with th muscainic cpton bonchial smooth muscl. Ca++ las is mdiatd by th scond mssng systm consisting IP3 (inositol tiphosphat) and DAG (diacylglycol).
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one clinical trial was conducted with atrovent nasal spray 0.
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