In patients receiving chloroquine therapy cases of cardiomyopathy have been reported, leading to heart failure, sometimes with fatal outcome see sections 4.
Information about Chloroquine.
Chloroquine may be used throughout pregnancy for the prophylaxis and treatment of malariaIf chloroquine resistance of the parasite is likely or has been demonstratedother drugs must be used.
Use of this drug is contraindicated in the presence of retinal or visual field changes either attributable to 4-aminoquinoline compounds or to any other etiologyand in patients with known hypersensitivity to 4-aminoquinoline compoundsHoweverin the treatment of acute attacks of malaria caused by susceptible strains of plasmodiathe physician may elect to use this drug after carefully weighing the possible benefits and risks to the patient.
Chemicallyit is 7-chloro-44diethylamino1-methylbutyl]aminoquinoline phosphate1:2and has the following structural formula:
What should I discuss with my healthcare provider before taking chloroquineAralen Phosphate
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a trend was however noticed for maintenance of decreased levels of ki67, cd69 and ccr5 in the gut of the chloroquine-treated animals, although the differences with values from the control group did not reach statistical significance.
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