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MusculoskeletalThe onset of scoliosis or worsening of a pre-existing scoliosis has been reportedUrogenitalSexual dysfunction in men and womenincluding decreased libido and orgasm dysfunctionhave been reportedErectile dysfunction in men has also been reportedPriapism has been reported following baclofen withdrawal.
Patients suffering from psychotic disordersschizophreniaor confusional states should be treated cautiously with LIORESAL INTRATHECAL and kept under careful surveillancebecause exacerbations of these conditions have been observed with oral administration.
DRUG INTERACTIONS There is inadequate systematic experience with the use of LIORESAL INTRATHECAL in combination with other medications to predict specific drug-drug interactionsInteractions attributed to the combined use of LIORESAL INTRATHECAL and epidural morphine include hypotension and dyspnea.
Precautions in special patient populationsCareful dose titration of LIORESAL INTRATHECAL is needed when spasticity is necessary to sustain upright posture and balance in locomotion or whenever spasticity is used to obtain optimal function and care.
Lioresal is indicated for the relief of spasticity of voluntary muscle resulting from such disorders asmultiple sclerosisother spinal lesionse.gtumours of the spinal cordsyringomyeliamotor neurone diseasetransverse myelitistraumatic partial section of the cord.
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lioresal also exerts an antinociceptive effect.
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