In this particular study, based on an overall number of 10 cases of liver injury associated with diclofenac, the adjusted odds ratio increased further with female gender, doses of 150 mg or more, and duration of use for more then 90 days.
Information about Diclofenac.
All eight NSAIDs are available on prescriptionwhile diclofenacnaproxen and ibuprofen are also available in lower dose over-the-counterOTCforms that can be obtained without a prescriptionPiroxicam is also available as an OTC topical medicine
Therapeutic Good’s AdministrationTGAPharmaceutical Benefits SchemePBSGuildLink DrugBank.
The TGA reviews found that there is a need to raise awareness among consumers and health professionals of the cardiovascular risks associated with NSAIDs and the additional hepatotoxicity risks for diclofenacincluding OTC versions of these medicines.
Riluzole Sandoz TabletsConsumer Medicines Information leaflets of prescription and over-the-counter medicines.
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some of the older nsaids, including meloxicam, diclofenac and ibuprofen, have a more selective cox 2 to cox 1 ratio, than other nsaids such as piroxicam or ketoprofen.
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