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Because serious GI bleedinghepatotoxicityand renal injury can occur without warning symptoms or signsconsider monitoring patients on long-term NSAID treatment with a CBC and a chemistry profile periodically.
NSAIDs are used to treat pain and rednessswellingand heatinflammationfrom medical conditions such as different types of arthritismenstrual crampsand other types of short-term pain.
Sandborn says his study enrolled 222 patientsall of whom had ulcerative colitis that was in remissionThe patients were randomly assigned to take either Celebrex or a placeboThe study was funded by Pfizerthe maker of CelebrexPfizer is a WebMD sponsor.
A history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Cardiovascular Thrombotic Eventssee WARNINGS AND PRECAUTIONSGI BleedingUlceration and Perforationsee WARNINGS AND PRECAUTIONSHepatotoxicitysee WARNINGS AND PRECAUTIONSHypertensionsee WARNINGS AND PRECAUTIONSHeart Failure and Edemasee WARNINGS AND PRECAUTIONSRenal Toxicity and Hyperkalemiasee WARNINGS AND PRECAUTIONSAnaphylactic Reactionssee WARNINGS AND PRECAUTIONSSerious Skin Reactionssee WARNINGS AND PRECAUTIONSHematologic Toxicitysee WARNINGS AND PRECAUTIONS
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