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For the reasons stated abovepatients and providers are advised to monitor for melanomas frequently and on a regular basis when using SINEMET for any indicationIdeallyperiodic skin examinations should be performed by appropriately qualified individualse.gdermatologists

Levodopa has been detected in human milkCaution should be exercised when SINEMET is administered to a nursing woman.

Swallow SINEMETwhole or as half tabletsonly if told by your doctorwith a glass of water.

If your doctor tells you to stop taking SINEMET or the tablets have passed their expiry dateask your pharmacist what to do with any that are left over.

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in these studies, using similar total daily doses of levodopa, plasma levodopa concentrations with sinemet cr fluctuated in a narrower range than with sinemet.

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