Hartfield aw, moore na, clifton pg 2003 effects of clozapine, olanzapine and haloperidol on the microstructure of ingestive behaviour in the rat.
Information about Olanzapine.
Olanzapine is indicated for the treatment of moderate to severe manic episode.
Appropriate clinical monitoring is recommendedincluding fasting blood lipid testing at the beginning ofand periodically duringtreatment.
Drug Reaction with Eosinophilia and Systemic SymptomsDRESSreported with olanzapine exposureDRESS may present with a cutaneous reactionsuch as rash or exfoliative dermatitiseosinophiliafeverand/or lymphadenopathy with systemic complications such as hepatitisnephritispneumonitismyocarditisand/or pericarditisDRESS is sometimes fataldiscontinue olanzapine if DRESS suspected.
Patients are at risk for severe sedationincluding comaor delirium after each injection and must be observed for at least 3 hours in registered facility with ready access to emergency response services.
DATA COLLECTION AND ANALYSISData were independently extractedFor homogeneous dichotomous data the random effects relative riskRRthe 95confidence intervalsCIandwhere appropriatethe number needed to treatNNTwere calculated on an intention-to-treat basisFor continuous data the reviewers calculated weighted mean differences.
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subchronic administration of olanzapine does not affect serum leptin, insulin, or adiponectin levels.
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