Levothroid levothyroxine sodium is a replacement for a hormone that is normally produced by your thyroid gland to regulate the body s energy and metabolism used to treat hypothyroidism low thyroid hormone .
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Occasionallychronic autoimmune thyroiditis may occur in association with other autoimmune disorders such as adrenal insufficiencypernicious anemiaand insulin-dependent diabetes mellitusPatients with concomitant adrenal insufficiency should be treated with replacement glucocorticoids prior to initiation of treatment with levothyroxine sodiumFailure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiateddue to increased metabolic clearance of glucocorticoids by thyroid hormonePatients with diabetes mellitus may require upward adjustments of their antidiabetic therapeutic regimens when treated with levothyroxinesee PRECAUTIONSDrug Interactions
Levothyroxine should not be used to treat obesity or weight problemsDangerous side effects or death can occur from the misuse of levothyroxineespecially if you are taking any other weight-loss medications or appetite suppressants.
In the treatment or prevention of various types of euthyroid goiterssee WARNINGS and PRECAUTIONSincluding thyroid nodulessee WARNINGS and PRECAUTIONSsubacute or chronic lymphocytic thyroiditisHashimoto’s thyroiditismultinodular goitersee WARNINGS and PRECAUTIONSandas an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.
Follow all directions on your prescription labelYour doctor may occasionally change your dose to make sure you get the best resultsDo not take this medicine in larger or smaller amounts or for longer than recommended.
Exercise caution when administering levothyroxine to patients with cardiovascular disorders and to the elderly in whom there is an increased risk of occult cardiac diseaseIn these patientslevothyroxine therapy should be initiated at lower doses than those recommended in younger individuals or in patients without cardiac diseasesee WARNINGSPRECAUTIONSGeriatric Useand DOSAGE AND ADMINISTRATIONIf cardiac symptoms develop or worsenthe levothyroxine dose should be reduced or withheld for one week and then cautiously restarted at a lower doseOvertreatment with levothyroxine sodium may have adverse cardiovascular effects such as an increase in heart ratecardiac wall thicknessand cardiac contractility and may precipitate angina or arrhythmiasPatients with coronary artery disease who are receiving levothyroxine therapy should be monitored closely during surgical proceduressince the possibility of precipitating cardiac arrhythmias may be greater in those treated with levothyroxineConcomitant administration of levothyroxine and sympathomimetic agents to patients with coronary artery disease may precipitate coronary insufficiency.
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