Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online, Advertising and sponsorship opportunities. This might not be very convenient for a couple of times I was forgetting about it in the afternoon or evening. In most cases, the main cause of premenstrual syndrome is a hormonecalled prolactin which gets secreted in higher levels than usual. Don't take evening primrose if you have a bleeding disorder. Last updated on February 28, 2020. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. In the 17th century, evening primrose oil became a popular folk remedy in Europe, where it was known as “King’s cure-all.” Today, evening primrose oil dietary supplements are promoted for atopic dermatitis (a type of eczema), rheumatoid arthritis, premenstrual syndrome (PMS), breast pain, menopause symptoms, and other conditions. This type of herbal supplement is known for relieving various symptoms of PMS.For example, it can make mood swings less severe and less common, while also reducing bloating and cramping. No toxicity, carcinogenicity, or teratogenicity has been reported. This product may be unsafe when used before surgery or other medical procedures. The typical content of gamma-linolenic acid (GLA) in the oil is 8% to 10%. Dosages in these trials ranged from 360 to 480 mg GLA daily. People take evening primrose oil orally to treat a wide variety of conditions. http://www.micromedexsolutions.com. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Evening primrose oil. Consider therapy modification.59, 60, 61, 62, Two clinical studies conducted in the 1980s among individuals with schizophrenia led to a concern that evening primrose oil might lower the seizure threshold. Evening primrose oil is the oil extracted from the seeds of the yellow evening primrose wildflower, Oenothera biennis. Evening primrose oil might increase the risk of pregnancy complications. Few adverse effects were noted in these trials, and there was no increase in blood glucose levels.43, 44, As a component of medical nutrition therapy for patients with type 2 diabetes, the American Diabetes Association Standards of Care (2014) recommends higher quality dietary fat intake, as an alternative to decreased fat intake, by replacing saturated and/or trans fats with mono- and poly-unsaturated fatty acids in the diet. After 4 months of blinded treatment, … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Excessive levels of the hormone prolactin may be responsible for many of the symptoms associated with PMS, although this is not the case for all women who suffer at that time of the month. Mucilage and tannin in the plant parts have been analyzed.2, Essential fatty acids are important as cellular structural elements and as precursors of prostaglandins. Bleeding may occur. It is reported useful for nursing moms who are trying to conceive. If you're planning to have surgery, stop taking evening primrose two weeks beforehand. One of the largest studies ever conducted on mastalgia randomized 555 women to one of four groups. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. This content does not have an English version. Micromedex 2.0 Healthcare Series. Evening primrose oil. The next box I order will be 1300mg. However, this relationship was not proven in a pharmacokinetic study in healthy participants.5, Atopic eczema/dermatitis syndrome has been recommended by an international task force to encompass all forms of eczema, including atopic dermatitis.67 A number of reviews and randomized clinical trials show a lack of support for the use of evening primrose oil for atopic dermatitis.6, 7, 8, 9 Many of the trials are of poor quality and have apparent issues of bias.9, 10, 11 In 2013, a Cochrane review evaluated 19 placebo-controlled, randomized clinical trials conducted in adults and children that assessed evening primrose oil for the treatment of signs and symptoms of eczema. Evening primrose oil (Oenothera biennis) comes from the seeds of a wildflower that grows throughout the United States. Evening primrose oil can be taken in liquid or pill form. The recommended dosage for evening primrose oil is 8 to 12 capsules each day. For sunburn, patients may take up to 8 capsules daily until the symptoms subside. Bleeding may occur. 5 Each woman took 4 g/d of capsules containing either evening primrose oil alone, evening primrose oil plus multivitamins, multivitamins alone, or placebo. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. That they look into natural treatments, such as evening primrose oil can be in... It is reported useful for nursing moms who are trying to conceive is. A wide variety of conditions nonprofit organization and proceeds from Web advertising help support our.. 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